O-propargyl-puromycín

Does anyone know whether "O-propargyl-puromycin", an isotope-free material to Stoleru, D., and Salic, A. 2012. Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin.

O-Propargyl-puromycin is a clickable form of the protein synthesis inhibitor puromycin. OP-puro is incorporated into nascent polypeptide chains where it forms covalent adducts and terminates chain elongation on the ribosome. It has been used in combination with fluorescent azides to image nascent proteins in various cells. An alkyne derivative of puromycin used to supervise newly protein synthesis, named O-propargyl-puromycin (OPP), is a potent protein synthesis inhibitor that stopping translation through be incorporated into the C-terminus of translating polypeptide chains. OPP can conjugate with nascent polypeptide chains thus constituting a covalent form. OPP O propargyl puromycin is an alkyne analog of puromycin that is efficiently incorporated into newly translated proteins in complete methionine containing media When used with Click iT Plus OPP Alexa Fluor Protein Synthesis assays or Alexa Fluor Picolyl Azide toolkits OPP provides a fast sensitive and non radioactive method for the detection of protein synthesis using fluorescence microscopy high content … O-propargyl-puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor.

11.05.2021

PML-NBs: 4 : 2012: Imaging protein synthesis in cells and tissues with an alkyne analog of puromycin. O-Propargyl-Puromycin Cat. No.: HY-15680 CAS No.: 1416561-90-4 Batch No.: 25014 Chemical Name: Adenosine, 3'-[[(2S)-2-amino-1-oxo-3-[4-(2-propyn-1-yloxy)phenyl]propyl]amino]-3'-deoxy-N,N-dimethyl-PHYSICAL AND CHEMICAL PROPERTIES Molecular Formula: C24H29N7O5 Molecular Weight: 495.53 Storage: Powder -20°C 3 years 4°C 2 years In solvent -80°C 10.01.2012 Recently, a clickable puromycin analog, O-propargyl-puromycin (OPP), was developed and applied to label the C-termini of nascent polypeptide chains (NPCs). Following affinity purification via a click reaction, OPP allows for a proteomic analysis of NPCs. O-propargyl-puromycin [MeSH concept] Semantic type(s) Antibiotic [Semantic type] Nucleic Acid, Nucleoside, or Nucleotide [Semantic type] Keyword's position in hierarchy(ies) : You can consult : All resources. or only the major.

O-Propargyl-puromycin (OPP) is cell-permeable alkyne analog of the protein synthesis inhibitor puromycin (Cat. No. 1860) that efficiently incorporates into newly translated proteins in complete methionine-containing media.

25.07.2016 Detection of O-propargyl-puromycin with SUMO and ubiquitin by click chemistry at PML-nuclear bodies during abortive proteasome activities. PML-NBs: 3 : 2016: Puromycin induces SUMO and ubiquitin redistribution upon proteasome inhibition.

O-Propargyl-Puromycin; Cat. No. : CS-6850: CAS No. : 1416561-90-4: Formula: C24H29N7O5: M. Wt. : 495.53 Solubility:

[1] reported a non-radioactive alternative to analyze newly synthesized proteins in cell culture and whole organisms that is based on O-Propargyl-puromycin, an alkyne analog of puromycin. O-Propargyl-puromycin is cell-permeable and incorporates into the C-terminus of translating polypeptide chains thereby stopping translation. O-propargyl-puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor.

OP-puro is incorporated into nascent polypeptide chains where it forms covalent adducts and terminates chain elongation on the ribosome.

No. 1860) that efficiently incorporates into newly translated proteins in complete methionine-containing media. Boc Sciences offers 1416561-90-4 O-Propargyl-puromycin in bulk, please inquire us to get a quote for 1416561-90-4 O-Propargyl-puromycin. O-Propargyl-puromycin is a clickable form of the protein synthesis inhibitor puromycin. OP-puro is incorporated into nascent polypeptide chains where it forms covalent adducts and terminates chain elongation on the ribosome. It has been used in combination with fluorescent azides to image nascent proteins in various cells.

O-Propargyl-puromycin is cell-permeable and incorporates into the C-terminus of translating polypeptide chains thereby stopping translation. O-propargyl-puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-propargyl-puromycin can be used to image and affinity-purify nascent proteins in cells and in animals. O-propargyl-puromycin inhibits protein synthes O-Propargyl-puromycin: Non-radioactive monitoring of nascent protein synthesis. The dynamics of global protein synthesis (both spatial and temporal) is an essential parameter to characterize the cellular response under various physiological and pathological conditions. A non-radioactive alternative to analyze newly synthesized proteins in cell culture and whole organisms that is based on O-Propargyl-puromycin, an alkyne analog of puromycin.

O-propargyl-puromycin, an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-propargyl-puromycin can be used to image and affinity-purify nascent proteins in cells and in animals. O-propargyl-puromycin inhibits protein synthes O-Propargyl-puromycin: Non-radioactive monitoring of nascent protein synthesis. The dynamics of global protein synthesis (both spatial and temporal) is an essential parameter to characterize the cellular response under various physiological and pathological conditions. A non-radioactive alternative to analyze newly synthesized proteins in cell culture and whole organisms that is based on O-Propargyl-puromycin, an alkyne analog of puromycin. O-Propargyl-puromycin is cell-permeable and incorporates into the C-terminus of translating … CAS: 1416561-90-4 O-Propargyl-puromycin (OPP) is cell-permeable alkyne analog of the protein synthesis inhibitor puromycin (Cat.

O. Molecular Weight: Chemical Composition: CAS Number: … O-propargyl-puromycin(cas 1416561-90-4) is an alkyne analog of puromycin, is a potent protein synthesis inhibitor. O-propargyl-puromycin. Known as: OP-puro National Institutes of Health Create Alert. Related topics. Related topics 2 relations. Broader (1) Puromycin. analogs & derivatives.

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In Vitro. O-propargyl-puromycin can be used to image and affinity-purify nascent proteins in cells and in animals. O-propargyl-puromycin inhibits protein synthesis, both in reticulocyte lysates and in cultured cells, displaying a potency two- to threefold lower than that of unmodified puromycin. O-propargyl-puromycin forms covalent conjugates with

In Vitro. O-propargyl-puromycin can be used to image and affinity-purify nascent proteins in cells and in animals. O-Propargyl-puromycin (OPP) is cell-permeable alkyne analog of the protein synthesis inhibitor puromycin (Cat. No. 1860) that efficiently incorporates into newly translated proteins in complete methionine-containing media.